Monday, December 30, 2019
The Physiological Effect Of Angiotensin Renin System
During my undergraduate years, I came across a drug class called Angiotensin Converting Enzyme (ACE) inhibitor. This medicine interferes in a production of angiotensin II via the enzyme inhibition, ultimately lowering the blood pressure. Understanding the physiological effect of angiotensin-renin system greatly fascinated me how our body is sophisticated in its structure and function, and it intrigued me further that our current knowledge allows us to design ACE inhibitor to combat high blood pressure. In ongoing pursuit of a pharmacist career, I learned that an application of medical knowledge such as ACE inhibitor involves much more complex issues. Before treating ACE inhibitor to patient, understanding the side effects, drug-drug interactions, and other therapeutic interactions is critical to ensure the safety and efficacy of the medicine. In this aspect, I find the role of pharmacist compelling in that the pharmacist is essential in informing and executing proper medication distr ibution to patients. Furthermore, pharmacy incorporates both the knowledge of chemistry with health care, which I am both profoundly dedicated with. In my high school years, as a member of Academy of Science and Medicine, I indulged myself in the environment of medical science. Developing knowledge about biotechnology such as PCR, gel-electrophoresis, and transformation inspired me to set my heart for health care field. However, with unfortunate financial circumstances in my family, thisShow MoreRelatedHypertension : Hypertension And Essential Hypertension Essay1171 Words à |à 5 Pagesdefined as an arterial blood pressure that is raised above 140/90 mm Hg (systolic/ diastolic BP). Hypertension can be classified into Secondary hypertension and Essential hypertension. When specific cause is evident but heredity, and various physiological parameters play a role in increasing blood pressure is known as Essential Hypertension. Secondary Hypertension is one where the cause is known. A ccording to WHO guidelines between 2006 and 2015, deaths due to cardiovascular diseases are expectedRead MoreThe Physiological Effects of Renovascular Hypertension (Renal Hypertension) on the Body1673 Words à |à 7 Pagesto the kidneysââ¬â¢ ability to synthesize glucose from amino acids. The final function of the kidneys is the production of specific hormones or enzymes, such as erythropoietin, which controls erythrocyte production, and renin, which is an enzyme that influences the formation of angiotensin (10). Renovascular hypertension is currently the most common type of secondary hypertension as it accounts for 1% to 5% of cases in the United States. Renovascular hypertension is a type of secondary hypertension becauseRead MoreWhat Are The Negative Effects Of Chemotherapy Related Diarrhoea741 Words à |à 3 PagesThe Negative Effects of Chemotherapy Related Diarrhoea on Systems Homeostasis Important information for new physiologists working with CRD affected patients Patients suffering from chemotherapy related diarrhoea (CRD) will face a multitude of social and physiological challenges, and itââ¬â¢s important to understand that the chronic nature of CRD is the basis for most of them. Within hours of the onset of symptoms, isotonic dehydration will rapidly lead to hypovolemia and consequently; tachycardia,Read MoreTypes Of Hypertension And Secondary Hypertension1434 Words à |à 6 Pagesthis number is expected to keep rising further increasing the risk for millions in developing cardiovascular disease. There are two main types of hypertension. Secondary hypertension is caused from an underlying disease in the adrenal or renal systems or by use of certain medications. It is resolved when the cause is treated or removed. Primary or essential hypertension is the most common type with the cause being unclear although the incidence is higher with age and weight. Pathophysiology Read MoreAtrap, And Angiotensin Receptor Associated Protein732 Words à |à 3 Pages Introduction: ATRAP, or Angiotensin Receptor Associated protein, is a cytoplasmic protein that is found to interact with the carboxyl-terminal domain of Angiotensin type 1 receptors (AT1) (Cui et al., 2000). ATRAP was discovered to have three hydrophobic domains located at the amino-terminal end and one long hydrophilic tail found at the carboxyl-terminal end (Lopez-Ilasaca et al., 2003). This 18-kDA protein is highly specific in itââ¬â¢s binding and is predicted to have three transmembrane domainsRead MoreThe Principles Of Homeostasis And The Contribution Of The Cardiovascular System1483 Words à |à 6 Pagesdescribe the principles of homeostasis, and the contribution of the cardiovascular system to homeostasis. Using the example of congestive heart failure (CHF), the causes and the consequences of a homeostatic imbalance in cardiac output will be explained. Homeostatic principles Homeostasis can generally be defined as the condition in which the bodyââ¬â¢s internal environment remains relatively constant within physiological limits [1]. This type of equilibrium is dynamic as the body is constantly subjectRead MoreQuestions On Urinary System Physiology1606 Words à |à 7 PagesPatho Review Questions for Urinary System Physiology 1. What are the principle organs of the urinary system? Kidneys 2. Accessory organs of the urinary system? Ureter, urinary bladder, and urethra 3. How do the right and left kidneys compare? The right kidney sits lower than the left kidney and is smaller due to the liver occupying the same space. 4. What are the muscles that that make up the bladder wall? - The detrusor muscle is smooth muscle that contracts to force urine out of the body;Read MoreThe Effect Of Salt Intake On Hypertensive Vs. Individuals4406 Words à |à 18 Pages Effect of Salt intake on Hypertensive vs. Normotensive Individuals Syed Muhammad Raza Zaidi, B.Sc., MD Candidate Medical University of Americas Syed Zaidi 42B-5305 Glen Erin Drive, Mississauga, ON L5M 5N7 Phone #: (647) 767-6347 Email: syedxeidi@gmail.com I would like to extend special thanks to all authors that have contributed to the intellectual property that was central to the compilation of this work. Mentor: Dr. Vivek Joshi Word Count: 4388 Hypothesis: Decreasing saltRead MoreThe Effects Of Water On The Body Weight996 Words à |à 4 PagesWater is about 60% of the adult human body weight. The relative importance of water is readily apparent through the role it plays in various systems of the body. The popular notion, therefore, exists that one must drink eight 8-oz glasses of water, which amounts to about 2 L, per day. Currently, the Institute of Medicine states that the total beverage intake for men should be about 13 cups or 3 L and for women 9 cups or 2.2 L (Water: How Muchâ⬠¦Ã¢â¬ ). The right amount of water one should drink eachRead MoreAn Outline Of An Assignment1966 Words à |à 8 Pages2007) Connecting History of Presenting Complaint Mr Jones requires regular review and management of his Essential Hypertension which was first diagnosed 5 years ago. He has been well maintained on lower than recommendation (NICE, 2011) dose of angiotensin converting enzyme inhibitor Lisinopril dihydrate. He has no other comorbidities. He comes to see me on a booked appointment for his 6 month review with 2 weekââ¬â¢s raised blood pressure readings taken twice a day at home (Appendix 3). His highest
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